Lab Staff

Katherine Rhodes, MA : Research & Network Facilitator

Katherine Rhodes, MA

Research & Network Facilitator

Katherine is the Research Facilitator for the Leducq Foundation Project, and is responsible for managing the finances and networking components of the project. Before this project began, she worked as research coordinator in women's health after she completed her Master's degree in Family Studies at UBC.

krhodes@brain.ubc.ca
Katherine Rhodes, MA : Research & Network Facilitator
Katherine Rhodes, MA

Katherine Rhodes, MA

Research & Network Facilitator

Katherine is the Research Facilitator for the Leducq Foundation Project, and is responsible for managing the finances and networking components of the project. Before this project began, she worked as research coordinator in women's health after she completed her Master's degree in Family Studies at UBC.

krhodes@brain.ubc.ca
Katherine Rhodes, MA
Veronica Galvin, BSc : Lab Assistant

Veronica Galvin, BSc

Lab Assistant

Veronica completed her BSc at Quest University Canada, with on cognitive neuroscience and consciousness.  During her undergraduate studies she developed a keen interest in glial cells and neuron-glia communication, and worked in two neuroscience laboratories as summer research assistants at Wesleyan University and Yale University in Connecticut learning various techniques in neurobiology.  She joined the MacVicar lab in the fall of 2012 hoping to gain more research experience while helping with various projects in the lab before looking into graduate programs.

veronica.galvin@gmail.com
Veronica Galvin, BSc : Lab Assistant
Veronica Galvin, BSc

Veronica Galvin, BSc

Lab Assistant

Veronica completed her BSc at Quest University Canada, with on cognitive neuroscience and consciousness.  During her undergraduate studies she developed a keen interest in glial cells and neuron-glia communication, and worked in two neuroscience laboratories as summer research assistants at Wesleyan University and Yale University in Connecticut learning various techniques in neurobiology.  She joined the MacVicar lab in the fall of 2012 hoping to gain more research experience while helping with various projects in the lab before looking into graduate programs.

veronica.galvin@gmail.com
Veronica Galvin, BSc

Associates

Hyun Beom Choi, PhD : Leducq Research Associate

Hyun Beom Choi, PhD

Leducq Research Associate

I am very interested in studying the mechanisms underlying metabolic communications between neuronal and glial cells. Astrocytes are proposed to maintain brain health by providing energy substrates to neurons from their glycogen stores and from glycolysis. However, little is known about the molecular pathways responsible for metabolic coupling between different cell types in the central nervous system. Currently, I am investigating the role of astrocytes in providing an energy sustrate to neurons in an activity dependent manner.

chb1212@gmail.com
Hyun Beom Choi, PhD : Leducq Research Associate
Hyun Beom Choi, PhD

Hyun Beom Choi, PhD

Leducq Research Associate

I am very interested in studying the mechanisms underlying metabolic communications between neuronal and glial cells. Astrocytes are proposed to maintain brain health by providing energy substrates to neurons from their glycogen stores and from glycolysis. However, little is known about the molecular pathways responsible for metabolic coupling between different cell types in the central nervous system. Currently, I am investigating the role of astrocytes in providing an energy sustrate to neurons in an activity dependent manner.

chb1212@gmail.com
Hyun Beom Choi, PhD
Jeff LeDue, MSc : Research Associate

Jeff LeDue, MSc

Research Associate

I completed my BSc in physics at Dalhousie University and pursued graduate studies at the University of Victoria working on novel wavefront sensors for Adaptive Optics at the Herzberg Institute of Astrophysics.  I transitioned from physical to biomedical science while working in the Nanoscience and Scanning Probe Microscopy group in the Physics Department at McGill University where we used combined Total Internal Reflection Fluorescence Microscopy and Atomic Force Microscopy to study inter and intracellular calcium signalling in osteoblasts and osteoclasts.  In my next position as Imaging Specialist for the Vision Science Core at the University of California, Berkeley, I supported the research of labs working on all aspects of vision and eye health, from the role of MyD88 in corneal barrier function to the neurobiology of the retina, with programming, data/image analysis and design and implementation of custom optical hardware.

At UBC I manage the In-vivo Imaging Core two photon microscopes in the Center for Disease Modelling and am responsible to the MacVicar lab as well as the lab of Prof. Timothy Murphy.  I am currently developing custom hardware for optogenetic brain mapping using laser stimulation and voltage sensitive dye imaging.

jledue@interchange.ubc.ca
Jeff LeDue, MSc : Research Associate
Jeff LeDue, MSc

Jeff LeDue, MSc

Research Associate

I completed my BSc in physics at Dalhousie University and pursued graduate studies at the University of Victoria working on novel wavefront sensors for Adaptive Optics at the Herzberg Institute of Astrophysics.  I transitioned from physical to biomedical science while working in the Nanoscience and Scanning Probe Microscopy group in the Physics Department at McGill University where we used combined Total Internal Reflection Fluorescence Microscopy and Atomic Force Microscopy to study inter and intracellular calcium signalling in osteoblasts and osteoclasts.  In my next position as Imaging Specialist for the Vision Science Core at the University of California, Berkeley, I supported the research of labs working on all aspects of vision and eye health, from the role of MyD88 in corneal barrier function to the neurobiology of the retina, with programming, data/image analysis and design and implementation of custom optical hardware.

At UBC I manage the In-vivo Imaging Core two photon microscopes in the Center for Disease Modelling and am responsible to the MacVicar lab as well as the lab of Prof. Timothy Murphy.  I am currently developing custom hardware for optogenetic brain mapping using laser stimulation and voltage sensitive dye imaging.

jledue@interchange.ubc.ca
Jeff LeDue, MSc

Fellows

Michael McFerrin, PhD : Postdoctoral Fellow

Michael McFerrin, PhD

Postdoctoral Fellow

My current research interests revolve around the increasing evidence that astrocytes not only provide important metabolic and homeostatic support to neurons, but play an active role in modulating neuronal activity and regulating blood flow. Astrocytes are sensitive to a variety of neurotransmitters and can respond with increases in intracellular calcium. My goal is to study the routes of calcium influx, and the downstream targets, to better understand the role of calcium signaling and mechanisms behind astrocytic modulation of blood flow and neuronal activity. I am currently developing tools to express genetically encoded calcium indicators specifically in astrocytes for use in two-photon laser scanning microscopy and animal models of gliosis, both as a result of injury and epilepsy, to study calcium signaling and astrocytic function in both the normal and pathologic states.

michael.mcferrin@ubc.ca
Michael McFerrin, PhD : Postdoctoral Fellow
Michael McFerrin, PhD

Michael McFerrin, PhD

Postdoctoral Fellow

My current research interests revolve around the increasing evidence that astrocytes not only provide important metabolic and homeostatic support to neurons, but play an active role in modulating neuronal activity and regulating blood flow. Astrocytes are sensitive to a variety of neurotransmitters and can respond with increases in intracellular calcium. My goal is to study the routes of calcium influx, and the downstream targets, to better understand the role of calcium signaling and mechanisms behind astrocytic modulation of blood flow and neuronal activity. I am currently developing tools to express genetically encoded calcium indicators specifically in astrocytes for use in two-photon laser scanning microscopy and animal models of gliosis, both as a result of injury and epilepsy, to study calcium signaling and astrocytic function in both the normal and pathologic states.

michael.mcferrin@ubc.ca
Michael McFerrin, PhD
Jingfei Zhang, PhD : Postdoctoral Fellow

Jingfei Zhang, PhD

Postdoctoral Fellow

Chronic activation of microglia is thought to be mediated in several pathological process. Microglias can be activated by harmful reagent such as lipopolysccharide (LPS) and beta amyloid. The release of cytokines from activated microglia are potential to generate synaptic disruption and neurodegeneration, leading to sickness behavior, memory deficits, and cognitive disfunctions.

In 2012 I completed my PhD work in field recording on hippocampal slices to study the mechanism of LPS induced cognitive deficits. Whole cell recording and behavior experiments will be involved in my study in the near future. My interests are also in the microglia based link among different physical stress such as hypoxia and inflammation.

reminiscing_fei@hotmail.com
Jingfei Zhang, PhD : Postdoctoral Fellow
Jingfei Zhang, PhD

Jingfei Zhang, PhD

Postdoctoral Fellow

Chronic activation of microglia is thought to be mediated in several pathological process. Microglias can be activated by harmful reagent such as lipopolysccharide (LPS) and beta amyloid. The release of cytokines from activated microglia are potential to generate synaptic disruption and neurodegeneration, leading to sickness behavior, memory deficits, and cognitive disfunctions.

In 2012 I completed my PhD work in field recording on hippocampal slices to study the mechanism of LPS induced cognitive deficits. Whole cell recording and behavior experiments will be involved in my study in the near future. My interests are also in the microglia based link among different physical stress such as hypoxia and inflammation.

reminiscing_fei@hotmail.com
Jingfei Zhang, PhD
Huili Han, PhD : Postdoctoral Fellow

Huili Han, PhD

Postdoctoral Fellow

Dr. Han completed her PhD in the Key Laboratory of Animal Models and Human Disease Mechanisms and Academy of Learning and Memory at the Kunming Institure of Zoology. She received a Canadian Heart & Stroke Postdoctoral Fellowship, and is one of the lab's Leducq Fellows.

Dr. Han's is interested in neurobiological mechanisms of aberrant memory by using behavioral, electrophysiological and molecular biological methods.

hlhan@interchange.ubc.ca
Huili Han, PhD : Postdoctoral Fellow
Huili Han, PhD

Huili Han, PhD

Postdoctoral Fellow

Dr. Han completed her PhD in the Key Laboratory of Animal Models and Human Disease Mechanisms and Academy of Learning and Memory at the Kunming Institure of Zoology. She received a Canadian Heart & Stroke Postdoctoral Fellowship, and is one of the lab's Leducq Fellows.

Dr. Han's is interested in neurobiological mechanisms of aberrant memory by using behavioral, electrophysiological and molecular biological methods.

hlhan@interchange.ubc.ca
Huili Han, PhD

Students

Ravi Rungta, BSc : PhD Student

Ravi Rungta, BSc

PhD Student

Ravi was awarded a CIHR Graduate Award in 2010 and is a Leducq Trainee.

My area of research interest is synaptic and non-synaptic control of neuronal excitability.  My projects include investigating a synaptic role for pannexin hemichannels, which our lab has shown opens during both stroke and epilepsy.  I am also looking into mechanisms for the uptake and release of adenosine, which inhibits transmitter release via  A1 receptors.

rlrungta@gmail.com
Ravi Rungta, BSc : PhD Student
Ravi Rungta, BSc

Ravi Rungta, BSc

PhD Student

Ravi was awarded a CIHR Graduate Award in 2010 and is a Leducq Trainee.

My area of research interest is synaptic and non-synaptic control of neuronal excitability.  My projects include investigating a synaptic role for pannexin hemichannels, which our lab has shown opens during both stroke and epilepsy.  I am also looking into mechanisms for the uptake and release of adenosine, which inhibits transmitter release via  A1 receptors.

rlrungta@gmail.com
Ravi Rungta, BSc
Lasse Dissing-Olesen, MSc : PhD Student

Lasse Dissing-Olesen, MSc

PhD Student

Lasse received his MSc from University of Southern Denmark. During his undergraduate he went on exchange at University of Miami, USA and at Cajal Institute in Madrid, Spain. He performed parts of the experiments for his master thesis at Novo Nordisk, Denmark. 
He is the recipient of a Canadian Heart & Stroke Doctoral Research Award and the 2010/11 North Award (highest rated HSFC Doctoral Research applicant from BC).
My research aims to discover novel interactions and ways of communication between neurons and glia. Currently, I'm investigating the activation of the brain's immune cells; the microglia in non-pathological paradigms using acute brain slices and an arsenal of different techniques: including two-photon laser scanning microscopy, electrophysiology, and enzyme based electrodes for specific in-situ quantification of target molecules. I strongly believe that by elucidating unknown mechanisms by which neurons crosstalk with glia we will contribute significantly to an enhanced understanding of the functional role of glia in the healthy as well as the diseased brain.

lassedolesen@gmail.com
Lasse Dissing-Olesen, MSc : PhD Student
Lasse Dissing-Olesen, MSc

Lasse Dissing-Olesen, MSc

PhD Student

Lasse received his MSc from University of Southern Denmark. During his undergraduate he went on exchange at University of Miami, USA and at Cajal Institute in Madrid, Spain. He performed parts of the experiments for his master thesis at Novo Nordisk, Denmark. 
He is the recipient of a Canadian Heart & Stroke Doctoral Research Award and the 2010/11 North Award (highest rated HSFC Doctoral Research applicant from BC).
My research aims to discover novel interactions and ways of communication between neurons and glia. Currently, I'm investigating the activation of the brain's immune cells; the microglia in non-pathological paradigms using acute brain slices and an arsenal of different techniques: including two-photon laser scanning microscopy, electrophysiology, and enzyme based electrodes for specific in-situ quantification of target molecules. I strongly believe that by elucidating unknown mechanisms by which neurons crosstalk with glia we will contribute significantly to an enhanced understanding of the functional role of glia in the healthy as well as the diseased brain.

lassedolesen@gmail.com
Lasse Dissing-Olesen, MSc
Rebecca Ko, BSc : PhD Student

Rebecca Ko, BSc

PhD Student

Rebecca received her B.Sc. (Hons) in Pharmacology from the University of British Columbia. During her undergraduate degree, she trained at Merck in West Point, Pennsylvania as part of the pharmacology Co-op program. She is currently undertaking a Ph.D. in Neuroscience. Her project involves understanding the interactions between astrocytes and neurons in complex behaviours.

ko.becca@gmail.com
Rebecca Ko, BSc : PhD Student
Rebecca Ko, BSc

Rebecca Ko, BSc

PhD Student

Rebecca received her B.Sc. (Hons) in Pharmacology from the University of British Columbia. During her undergraduate degree, she trained at Merck in West Point, Pennsylvania as part of the pharmacology Co-op program. She is currently undertaking a Ph.D. in Neuroscience. Her project involves understanding the interactions between astrocytes and neurons in complex behaviours.

ko.becca@gmail.com
Rebecca Ko, BSc
Aqsa Malik, MSc : PhD Student

Aqsa Malik, MSc

PhD Student

Aqsa compeleted her Master of Science degree in the Department of Cell & Systems Biology and Collaborative Program in Neuroscience at the University of Toronto before she joined Dr. MacVicar's Lab. Currently funded by NSERC, her awarded funding includes the Ontario Graduate Scholarship, the Vietnamese-Canadian Community Graduate Award in Zoology, and the Helen Sawyer Hogg Graduate Award.

aqsa.malik@utoronto.ca
Aqsa Malik, MSc : PhD Student
Aqsa Malik, MSc

Aqsa Malik, MSc

PhD Student

Aqsa compeleted her Master of Science degree in the Department of Cell & Systems Biology and Collaborative Program in Neuroscience at the University of Toronto before she joined Dr. MacVicar's Lab. Currently funded by NSERC, her awarded funding includes the Ontario Graduate Scholarship, the Vietnamese-Canadian Community Graduate Award in Zoology, and the Helen Sawyer Hogg Graduate Award.

aqsa.malik@utoronto.ca
Aqsa Malik, MSc